Update of the Scientific Opinion on opium alkaloids in poppy seeds.

However, a highly significant increase in the mutation frequency at the hprt locus was observed after treatment of human T‐cells for 3–4 days (Shafer et al., 1994 ).

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The CONTAM Panel noted a large variation in the alkaloid profile of the available poppy seed samples and observed a clear trend of association between the country of origin of the poppy seeds and high median morphine concentrations.

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