Germline variants in DNA repair genes associated with hereditary breast and ovarian cancer syndrome: analysis of a 21 gene panel in the Brazilian population.

BMC Med Genomics · 2020 · PMC7011249 · PMID 32039725

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showed a trendno p-value reported

Surprisingly, the patients that presented pathogenic variants in BRCA1/BRCA2 showed a trend towards better survival with most of cases that died being the ones that presented VUS, benign or no variants in BRCA1/BRCA2 genes (Fig. 5 ).

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