Although MnTnBuOE-2-PyP + I-131-treated animals were not significantly different from controls, these mice showed a trend of reduced white blood cell counts (Fig. 4 b); however, the WBC counts were still in normal range (6.25–11.13 K/μl, Charles River’s website https://www.criver.com/sites/default/files/resources/C57BL6MouseModelInformationSheet.pdf ).
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MnTnBuOE-2-PyP treatment protects from radioactive iodine (I-131) treatment-related side effects in thyroid cancer.
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