A similar effect of Nrf2 suppression was observed with DU145 cells, where although the HIF-1α induction in response to IGF-1 was three-fold, this did not reach statistical significance ( Figure 3 A).
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IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β-Nrf2-BNIP3 Pathway.
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