Fat mass and obesity-associated gene polymorphisms, pre-diagnostic plasma adipokine levels and the risk of colorectal cancer: The Japan Public Health Center-based Prospective Study.

With regard to rs8050136, eight studies have investigated its effect on colorectal [ 25 ], endometrial [ 11 , 26 ], pancreatic [ 27 , 28 ], prostate [ 29 ], thyroid [ 30 ], and melanoma skin cancers [ 31 ], among which two studies showed a nominally significant association with cancers of the pancreas [ 28 ] and thyroid [ 30 ] in the main analysis.

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