The expression level of the Wnt transcription factor Tcf4 was lowest in the WD group ( Figure 6 C, 26.7%, p < 0.05) similarly with the Wnt activating co-receptor and Wnt target gene Lgr5 , although this did not reach statistical significance ( Figure 6 D).
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Switching to a Healthy Diet Prevents the Detrimental Effects of Western Diet in a Colitis-Associated Colorectal Cancer Model.
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