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A new mechanism for cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models.

Br J Pharmacol · 2020 · PMC7024701 · PMID 31693171

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showed a trendno p-value reported
Although we were unable to detect homocysteine in cells, cysteine levels showed a trend for a CBD‐dependent reduction in wild‐type cells that was absent in the gcvH1 − mutant, also consistent with a role for CBD in regulating GCS‐dependent one‐carbon metabolism.

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