Distinct HR expression patterns significantly affect the clinical behavior of metastatic HER2+ breast cancer and degree of benefit from novel anti-HER2 agents in the real world setting.

Int J Cancer · 2020 · PMC7027476 · PMID 31330065

Europe PMC DOI

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0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

Brain metastases were more frequently observed in patients with ER or PgR‐positive BCs and in HRs negative tumors than in patients with a TP subtype, even though this difference did not reach statistical significance (29.6 and 27.8%, respectively, vs . 20.8%; p = 0.06).

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