In the bone marrow reconstitution model described above, we found that there were significantly more CD11c + DCs in the tumors and tumor draining lymph nodes, while the CD11c + cells in the spleen exhibited a similar trend but the increase did not reach statistical significance ( Figure 3(a )) in miR-155tg-BMT mice.
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Overexpression of microRNA-155 enhances the efficacy of dendritic cell vaccine against breast cancer.
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