Separate analysis of European countries with three or more cohorts: Italy (Dardano et al., 2009 ; Ghiadoni et al., 2013 ; Sanz et al., 2014 ), Denmark (Ohlendorff et al., 2007 ; Hansen et al., 2008 ; Husted et al., 2013 ), and the United Kingdom (Starczynski et al., 2003 ; Zhang et al., 2003 ; Sellick et al., 2004 ), numbering three, three, and four cohorts respectively, showed a trend of increase in 1513CC P2RX7 frequency with age.
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