In primary cortical neurons, the levels of miR-26a showed a trend towards a decrease from the time of plating, which stabilised towards later stages of culture (DIV 9), when fast axonal growth starts to decline and synaptic maturation begins ( Chiappalone et al., 2006 ; Dotti et al., 1988 ; Opitz et al., 2002 ).
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Spatiotemporal regulation of GSK3β levels by miRNA-26a controls axon development in cortical neurons.
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