Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin.

J Am Heart Assoc · 2020 · PMC7033859 · PMID 32000579

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showed a trendP =0.07so close (0.05 < p ≤ 0.1)

Furthermore, cl‐OPN/FL‐OPN showed a trend ( P =0.07; N=28; Wilcoxon matched‐pairs signed rank test) to be higher in plasma from the coronary sinus versus plasma from the radial artery, indicating that osteopontin might be cleaved locally in the pressure‐overloaded human heart.

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