Prevention and mitigation of congenital toxoplasmosis. Economic costs and benefits in diverse settings.

According to a multicenter randomized trial in France, therapy with PS seems to be more effective than spiramycin therapy in the prevention of transmission of infection to the fetus, although the difference did not reach statistical significance (probably due to an insufficient number of pregnant women with seroconversion) ( Mandelbrot et al., 2018 ).

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