WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication.

Importantly, expression of an intronless TUBGCP6 transgene increased the fraction of cells with a normal centriole content 48 h after RNAi-mediated depletion of SLU7 or PRPF8, although for PRPF8 this increase did not reach statistical significance ( Fig. 8, E and F ).

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