Moreover, developmental up-regulation of KCC2 mRNA and protein levels in brain lysates was also comparable between genotypes, despite the observation that dendritic staining of KCC2 protein was slightly higher (∼1.14×, did not reach statistical significance) in 7-DIV Ecm29 −/− compared with wild-type neurons ( Fig. 3 , C2 and C3; and Fig.
← all excerpts
Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.
1
—
—