These findings were further reinforced by the RSA 0-3 h 50% assay, which showed a trend similar to that for RSA 0-3 h : all parasites with introduced PfK13 mutations had increased RSA 0-3 h 50% values, but the increase was significant only in parasites with the N458Y and C580Y mutations.
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Role of Plasmodium falciparum Kelch 13 Protein Mutations in P. falciparum Populations from Northeastern Myanmar in Mediating Artemisinin Resistance.
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