After treatment, Chao 1 values decreased significantly ( p = 0.02631) in the responder group, but there was no significant difference in the nonresponder group ( p = 0.3531), with an increasing trend in all samples and paired samples ( Figure 1a ).
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Composition of fecal microbiota in low-set rectal cancer patients treated with FOLFOX.
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There was a clear trend towards a higher average distance in the responder group, though the difference was not significant ( p = 0.1341, Figure 1d ).