Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells.

Sci Rep · 2020 · PMC7046667 · PMID 32107448

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showed a trendno p-value reported

IOP elevation in Brown Norway rats showed a trend towards decreased expression of ATP5H.

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a decreasing trendno p-value reported

an increasing trendno p-value reported

On the other hand, an increasing trend in the expression of FOXO1 (31%) and Map3K11 (179%) genes and a decreasing trend in the expression of Cox17 (17%) and G6PD (15%) genes were observed in ET-1 treated RGCs (Fig. 4 ).

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