A revised model of TRAIL-R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis.

EMBO Rep · 2020 · PMC7054686 · PMID 32009295

Europe PMC DOI

hedged sentence

0.0006

closest p · 0.0× alpha

0.0006

boldest claim

The sentences

highly significantP = 0.0006actually significant

approached significanceP = .0506so close (0.05 < p ≤ 0.1)

Of note, a highly significant correlation was observed between caspase‐8 activity and the ratio of FADD:FLIP(L) (Pearson's r = 0.91; P = 0.0006; Fig 1 F), while the correlation between caspase‐8 activity and the ratio of total caspase‐8:FLIP(L) approached significance (Pearson's r = 0.67; P = .0506).

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