nominally significantP < 10 −3
2015 ) sequenced the genomes and transcriptomes of the O and B lines and assessed the genetic divergence between them, identifying 6,394 single nucleotide polymorphisms (SNPs) in or near 1,925 genes with nominally significant ( P < 10 −3 ) allele frequency differences, nearly 300 of which showed gene expression changes consistent with delayed senescence between young and old flies of the O and B lines.