Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes.

Conversely, following VAMP4 depletion, insulin still appeared to increase GLUT4 in the plasma membrane, although the increase did not reach statistical significance ( Fig. 4C ; ~1–7-fold, compared to ~3-fold in control cells, p = 0.18).

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