RESULTS Rbp2 absence predisposes to excessive adiposity During earlier studies of Rbp2 −/− mice ( 24 ), we noticed a trend for 3- to 4-month-old male Rbp2 −/− mice to have greater body weights than matched wild-type (WT) mice when the mice were maintained on a conventional chow diet; this trend did not reach statistical significance.
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Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight.
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