Recent findings in the genetics and epigenetics of asthma and allergy.

For anti-IL-5, a GWAS using data from clinical studies on mepolizumab (DREAM and MENSA), was recently published, and there is a clear trend (which is just not significant after correction for multiple testing) towards an association between the prevention of exacerbation on mepolizumab and a locus on chromosome 6 harboring UTRN and EPM2A and a further locus on chromosome 9 which included different type 1 Interferon genes such as IFNA14 [ 103 ].

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