Barely Significant
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Association between biochemical control and comorbidities in patients with acromegaly: an Italian longitudinal retrospective chart review study.

J Endocrinol Invest · 2020 · PMC7067716 · PMID 31741320

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Biochemical control was significantly associated with a lower hazard of diabetes (HR = 0.36, 95% CI 0.15; 0.83) and cardiovascular system disorders (HR = 0.54, 95% CI 0.31; 0.93), and a higher hazard of certain types of arthropathy (HR = 1.68, 95% CI 1.04; 2.71); associations for other comorbidities did not reach statistical significance.

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