Some questions and suggestions remain, How is it possible that Calsurf is marketed without any preclinical or clinical studies? For bovine or calf derived surfactant there is enough evidence and clinical studies, how does Calsurf relate to these products? Line 351-352 PEEP or no PEEP, If I look at figure 3, I see, possibly not significant, a positive effect of PEEP on the Cdyn.
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In vitro characterization and in vivo comparison of the pulmonary outcomes of Poractant alfa and Calsurf in ventilated preterm rabbits.
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