nearly significantp = 0.05
Also at the beginning of the study, the median sIgE value in response to rMal d 1 was 0.99 kU/L (range 0.04–94.60 kU/L) The patients showed a significant decrease of the median sIgE in response to Bet v 1 (10.60 to 5.19 kU/L; p = 0.01) and a nearly significant decrease of sIgE in response to rMal d 1 (0.99 to 0.61 kU/L; p = 0.05) after 2 years of BP-AIT ( Figure 2 ).