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Global Trends and Forecast of the Burden of Adverse Effects of Medical Treatment: Epidemiological Analysis Based on the Global Burden of Disease Study.

Cureus · 2020 · PMC7071843 · PMID 32195068

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an increasing trendno p-value reported
However, countries across the different regions, such as Ukraine [55.41% (37.44 to 73.37), Australia [24.02% (6.24 to 41.79), Sweden [14.49% (−3.46 to 32.44)], Japan [13.91% (−4.58 to 32.4)], United Kingdom [12.34% (−0.28 to 24.96)], and the US [10.14% (−5.92 to 26.2)] demonstrated an increasing trend in DALY between 1990 and 2017 (Table 2 and Figure 1 ).

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a negative trendno p-value reported
The global percentage of change in DALY showed a negative trend of −26.06 % (−41.52 to −10.59) across all WHO regions between 1990 and 2017.

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