Dill Extract Induces Elastic Fiber Neosynthesis and Functional Improvement in the Ascending Aorta of Aged Mice with Reversal of Age-Dependent Cardiac Hypertrophy and Involvement of Lysyl Oxidase-Like-1.

Biomolecules · 2020 · PMC7072659 · PMID 31979322

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Ex Vivo Response of Ascending Aorta Segments to Vasoactive Agents A strong trend towards an age-dependent decrease in the phenylephrine (PE)-induced vasoconstriction was observed in untreated animals: the aortic diameter decrease was of 17% in aged mice compared to 20% in adult animals (one-way ANOVA, p = 0.06; Figure 6 A).

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