a strong trendp = 0.070
Expression of miRNA-221 was not correlated with OS in the present patient cohort, however, in patients without neoadjuvant treatment miRNA-221 positive tumors showed a strong trend towards shortened OS ( p = 0.070) with a median OS of 64.0 months in miRNA-221 negative patients (95%CI not calculable) compared to a median OS of 22.1 month (95%CI 13.3–30.8 months).