Adiponectin Facilitates Postconditioning Cardioprotection through Both AMPK-Dependent Nuclear and AMPK-Independent Mitochondrial STAT3 Activation.

Adiponectin and Ischemic Postconditioning Exerted Distinct Effects on Cardiac AMPK and STAT3 Activation In Vivo As shown in Figure 4 , postischemic myocardial STAT3 activation (at Tyr705 and Ser727) was slightly increased but this increase did not reach statistical significance (Figures 4(a) and 4(b) ).

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