Background Diet Influences TMAO Concentrations Associated with Red Meat Intake without Influencing Apparent Hepatic TMAO-Related Activity in a Porcine Model.

A near-significant difference was found between pigs fed chicken combined with prudent background diet (1.54 Mm) and pigs fed red meat combined with western background diet (3.38 Mm) (Tukey’s HSD test, p = 0.06).

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The observed correlations in this exploratory approach, investigating potential relationships between TMAO generation and the microbial community, require a careful interpretation because of the borderline significance of the correlations and the absence of correction for multiple testing.

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