While all lots of D35 induced similar levels of CXCL10, the ultrapure oligos induced significantly lower level of IFNα and IL6 as well as a trend towards lower levels of IFNγ that did not reach statistical significance but could be clinically relevant ( Fig 1C ).
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CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis.
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