In our current studies, differences in the expression levels of SERCA2 between the NTG/PLN and TG/PLN groups did not reach significance, although we saw a clear trend toward lower levels in the TG/PLN group with a significant difference between the TG/PLN and NTG/PLNKO groups.
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Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response.
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