Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine.

Drug Metab Dispos · 2020 · PMC7076527 · PMID 31959703

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

moderately significantP = 0.058so close (0.05 < p ≤ 0.1)

The abundance of both proteins was higher in jejunum, with the difference considered significant for cadherin-17 (Mann-Whitney U test, P = 0.03) and moderately significant for Na + /K + -ATPase (Mann-Whitney U test, P = 0.058). mRNA expression relative to the reference gene GAPDH was determined for all transporters with the exception of SLCO1A2 (OATP1A2) and ATP1A1 (Na + /K + -ATPase).

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