COL1A1 expression in the pcDNA3.1‐Smad6+ si‐Foxf2‐1415 and pcDNA3.1‐Smad6+ si‐Foxf2‐650 groups was lower than that in the pcDNA3.1‐Smad6 group, but the difference did not reach statistical significance ( P > .05) (Figure 3 A). 3.2.2 Protein expression of Foxf2, Smad6, COL5A2, COL1A1, FN and α‐SMA in each group The results of Western blot analysis of the protein expression of Foxf2, Smad6, COL5A2, COL1A1, FN and α‐SMA in each group are shown in Figure 3 B.
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Foxf2 and Smad6 co-regulation of collagen 5A2 transcription is involved in the pathogenesis of intrauterine adhesion.
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