Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis.

Sci Rep · 2020 · PMC7078222 · PMID 32184434

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0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

showed a trendp = 0.056so close (0.05 < p ≤ 0.1)

HDAC inhibition via sodium butyrate (SB) showed a trend (p = 0.056) towards increased p53 acetylation, whereas Rhein treatment moderately but significantly enhanced p53 acetylation (1.2-fold; p < 0.05) (Fig. 4B ).

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