However, because the number of PTC samples included in the methylation analysis was very small and the hypermethylated CpG site did not reach statistical significance, it needs to be confirmed by pyrosequencing.
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Downregulation of SMOC2 expression in papillary thyroid carcinoma and its prognostic significance.
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The sentences
Interestingly, SMOC2 was identified as a risk locus for autoimmune thyroid disease 2 and SMOC2 single nucleotide polymorphism showed a marginally significant association in female autoimmune thyroid disease patients 3 .