MTHFR Ala222Val polymorphism and clinical characteristics confer susceptibility to suicide attempt in chronic patients with schizophrenia.

In the binary logistic regression model for associations with suicide attempt, education (OR = 0.89, 95% CI [0.82, 0.98], Wald χ 2 = 5.6, p = 0.018), PANSS depression factor (OR = 1.08, 95% CI [1.03, 1.13], Wald χ 2 = 11.04, p = 0.001), number of cigarettes smoked per day (OR = 1.20, 95% CI [1.18, 1.52], Wald χ 2 = 4.9, p = 0.043), and drinking status (OR = 0.40, 95% CI [0.24, 0.66], Wald χ 2 = 13.0, p < 0.001) remained significant and MTHFR Ala222Val polymorphism (OR = 1.72, 95% CI [0.94, 3.2], Wald χ 2 = 3.1, p = 0.07) approached significance.

also in 8,237 other papers