Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aβ42 decrease with age, whereas NT1 tau and NfL increase.

Alzheimers Res Ther · 2020 · PMC7081580 · PMID 32192521

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

There was a strong tendency for the DS/control Aβ42 ratio to be lower in the oldest group (> 50 years) compared to youngest group (0–10 years); however, this did not reach statistical significance (1.6 vs. 1.4, p = 0.08).

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