KEYNOTE-407: changing the way we treat stage IV squamous non-small cell lung cancer.

While exploratory analysis by histology did not suggest a significant OS benefit for squamous histology in this high PD-L1 group, there was a strong trend towards significance [HR 0.56 (95% CI, 0.23–1.37)] which may have been limited by the small sample size (n=50) ( 26 ).

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