Prospective Cohort Study of Childhood-Onset Stargardt Disease: Fundus Autofluorescence Imaging, Progression, Comparison with Adult-Onset Disease, and Disease Symmetry.

9 , 41 Despite the mean rate of progression being notably higher in children compared with adults with adult-onset (0.68 compared with 0.40 mm 2 /year), this did not reach statistical significance; this may likely be because of the high variation in the children group (SD, 0.72 mm 2 /year)—with childhood-onset disease being highly heterogeneous in terms of progression rates ( Figure 7 , Figure 9 ).

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