The escalated BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) regimen developed by the German Hodgkin Study Group (GHSG) is more effective than ABVD in terms of tumor control with consistent improvements in progression-free survival (PFS) when compared with ABVD, correlating with a trend towards increased overall survival (OS) that did not reach statistical significance in direct head to head comparisons [ 22 , 31 , 32 , 33 ].
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