Central CYP1B1 (Cytochrome P450 1B1)-Estradiol Metabolite 2-Methoxyestradiol Protects From Hypertension and Neuroinflammation in Female Mice.

Hypertension · 2020 · PMC7098446 · PMID 32148125

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

showed a trendP =0.054so close (0.05 < p ≤ 0.1)

ICV-E2 showed a trend of not reducing the effect of hexamethonium in OVX- Cyp1b1 +/+ mice with ICV-injected siRNA-COMT ( P =0.054; Figure 1 E).

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