Pharmacotherapy for hypertension in Sub-Saharan Africa: a systematic review and network meta-analysis.

BMC Med · 2020 · PMC7099775 · PMID 32216794

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Although combination therapy showed a trend towards superiority with SBP/DBP (− 8.66; 95% CI − 18.72, 1.40/− 6.11; 95% CI − 9.15/− 3.07), the majority of this effect was from a small study of 31 participants comparing methyldopa with a beta-blocker and diuretic combination [ 33 ].

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