Barely Significant
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The role of genetic variants in human longevity.

Ageing Res Rev · 2010 · PMC7105197 · PMID 20708717

Europe PMCDOI
2
hedged sentences
0.0005
closest p · 0.0× alpha
0.0005
boldest claim

The sentences

highly significantp < 0.0005actually significant
In particular, obtained from an allele-based case–control comparison, the top-ranking SNP, rs3800231, of FOXO3A had a highly significant ( p < 0.0005) OR of 1.42 (CI: 1.18–1.70).

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showed a trendno p-value reported
However, the three top-ranking SNPs (rs3800231, rs7762395, and rs768023) did not present a statistically robust replication result, and only showed a trend for the association with longevity in the French sample consisting of 535 centenarians (mean age 103.8 years) ( Flachsbart et al., 2009 ).

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