Some of these subgroup analyses (eg, the RSV group) did not reach statistical significance, probably because of the lack of power from dividing the main study group into smaller subgroups.
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Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants.
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The sentences
The ORMDL3 TT genotype was also significantly associated with the development of acute severe bronchiolitis during the first 2 years of life (cases vs control subjects, 49% vs 27%; P = .008), whereas male sex (cases vs control subjects, 65% vs 49%; P = .07) and young age at the start of day care (median age at start for cases vs control subjects, 296 vs 341 days; P = .08) were borderline significant.