Barely Significant
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Virus-like particles: the new frontier of vaccines for animal viral infections.

Vet Immunol Immunopathol · 2012 · PMC7112581 · PMID 22705417

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a clear trendno p-value reported
Currently, there is a clear trend towards the establishment of VLPs as a powerful tool for vaccine development.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.