The ACTB Variants and Alcohol Drinking Confer Joint Effect to Ischemic Stroke in Chinese Han Population.

The Interaction Analysis between ACTB rs852426 and Drinking The analysis stratified by never, light-to-moderate drinking and heavy drinking status indicated that the rs852426 variation had a protective effect on stroke in subjects with the light-to-moderate or heavy drinking habit, the HRs (95% CIs) were 0.523 (0.174−1.571) and 0.485 (0.176−1.336), although the p values did not reach statistical significance ( p values were 0.248 and 0.162).

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