Although inconclusive, the ADVANCE study, a phase 4 randomized clinical trial [ 22 ], showed a trend towards slower progression of cardiovascular calcifications in subjects treated with cinacalcet and low doses of active vitamin D, as compared to subjects treated with varying doses of vitamin D as monotherapy [ 22 ].
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New scenarios in secondary hyperparathyroidism: etelcalcetide. Position paper of working group on CKD-MBD of the Italian Society of Nephrology.
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