Individual and joint effects of metformin and statins on mortality among patients with high-risk prostate cancer.

Among patients with Stage IV PCa, data suggest there might be some synergistic effect between statin and metformin (HR, 0.93 for metformin alone, 0.82 for statin alone, and 0.66 for metformin plus statin) although this interaction did not reach statistical significance ( P interaction = .18) (Table S1 ).

also in 111,027 other papers